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Genomic Classification and Clinical Outcome in Rhabdomyosarcoma: A Report From an International Consortium.

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J Clin Oncol2021PMID 34166060PMC8425837stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

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Linked entities

Linked entities (5)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Validated 5

Curated evidence

Evidence citing this paper (3)

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
34166060
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–3 of 3 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
MYOD1 L122R1
(prognostic)RhabdomyosarcomaPrognosticBSupports Poor Outcome4accepted
EID9532

This study evaluated 641 cases of rhabdomyosarcoma (RMS), enrolled on Children’s Oncology Group trials (1998-2017) and UK malignant mesenchymal tumor and RMS2005 trials (1995-2016), for mutations in 3… (full text at CIViC)

PMID 34166060 · Shern et al., 2021 · Open in CIViC

civic
MYOD1 MYOD1 L122R1
(prognostic)RhabdomyosarcomaPrognosticBSupports Poor Outcome4rejected
EID9531

This study evaluated 641 cases of rhabdomyosarcoma (RMS), enrolled on Children’s Oncology Group trials (1998-2017) and UK malignant mesenchymal tumor and RMS2005 trials (1995-2016), for mutations in 3… (full text at CIViC)

PMID 34166060 · Shern et al., 2021 · Open in CIViC

civic
TP53 ALTERATION1
(prognostic)RhabdomyosarcomaPrognosticBSupports Poor Outcome4accepted
EID9594

This study evaluated 641 cases of rhabdomyosarcoma (RMS) that were enrolled in the Children’s Oncology Group (COG) trials from 1998 to 2017 and the UK malignant mesenchymal tumor and RMS2005 trails fr… (full text at CIViC)

PMID 34166060 · Shern et al., 2021 · Open in CIViC

civic