Publication
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerAcute Myeloid Leukemia with CEBPA Mutationcivic_curation1.00
- geneCEBPAcivic_curation1.00
- variantCEBPA Mutationcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 31784538
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CEBPA Mutation2 | ||||||||
| (diagnostic) | Acute Myeloid LeukemiaCURATED_BROADER | Diagnostic | D | Supports Negative | 3 | submitted | EID12175In this 2019 study, the authors investigated how the order of CEBPA mutations influences AML progression in mice that phenocopies the human disease transcriptionally and morphologically. The study rev… (full text at CIViC) PMID 31784538 · Braun et al., 2019 · Open in CIViC | civic |
| 〃 | Acute Myeloid Leukemia with CEBPA MutationALIAS | Diagnostic | D | Supports Positive | 3 | accepted | EID12200In this 2019 study, the authors investigated the diagnostic significance of CEBPA mutations in AML by analyzing how the order of these mutations influences disease development in a mouse model that re… (full text at CIViC) PMID 31784538 · Braun et al., 2019 · Open in CIViC | civic |