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Genotype-phenotype correlations in Chinese von Hippel-Lindau disease patients.

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Oncotarget2017PMID 28388566PMC5503545stubpubmedProvenance
Source
PubMed
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Run
ING-CIVIC-20260908-000001
Published

Abstract

Abstract (excerpt)

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Linked entities

Linked entities (3)

How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.

Validated 3

Curated evidence

Evidence citing this paper (67)

50 items per page.

civicProvenance
Source
CIViC — Clinical Interpretation of Variants in Cancer
Dataset
CIViC evidence items
Version
civic-2026-09-08
Retrieved
Sep 8, 2026
Layer
normalized (units and labels harmonized; values unchanged)
Evidence
expert curation
License
CC0 1.0
PMID
28388566
Run
ING-CIVIC-20260908-000001
Open at source
CuratedShowing 1–50 of 67 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.
TherapyCancerTypeLevelDirection · significanceRating (1–5)StatusEvidenceSource
VHL 3'UTR alteration (c.*70C>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6846

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL 3'UTR alteration (c.*70C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Predisposition2submitted
EID10647

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL C162* (c.486C>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6839

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL C162W (c.486C>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6837

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL C162Y (c.485G>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6838

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL D92fs (c.275delinsCC)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6809

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL E134_V142del (c.402_428del)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6825

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL E160fs (c.480delG)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6834

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL E189_D190del (c.565_570delGAAGAC)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6845

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL E94* (c.280G>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6810

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Exon 1-2 Deletion1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6848

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Exon 1-3 Deletion1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6849

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Exon 1 Deletion1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6847

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL EXON 2-3 DELETION1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6851

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Exon 2 Deletion1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6850

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Exon 3 Deletion1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6852

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL F136C (c.407T>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6827

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL F76del (c.227_229del)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6794

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL H110PFS*49 (c.329delA)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6815

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL H115FS (c.343delC)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6820

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL H115R (c.344A>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6819

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL I151F (c.451A>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6832

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL I151N (c.452T>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Predisposition3submitted
EID10525

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL I151S (c.452T>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6833

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL L135* (c.404T>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6826

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL L178R (c.533T>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6844

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL L85P (c.254T>C)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6800

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL L89P (c.266T>C)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6807

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL N78S (c.233A>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6795

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL N90I (c.269A>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6808

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL P146Gfs*14 (c.435_436insGG)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6829

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL P86L (c.257C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6802

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL P86R (c.257C>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6803

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL P86S (c.256C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6801

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL P97Afs*35 (c.287_288insA)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6812

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Q145fs (c.433_437delCAGCC)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6828

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Q73* (c.217C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6793

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL Q96* (c.286C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6811

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R161* (c.481C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6835

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R161Q (c.482G>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6836

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R167P (c.500G>C)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6842

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R167Q (c.500G>A)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6841

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R167W (c.499C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6840

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R69AFS*63 (c.204_205insG)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6792

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL R82P (c.245G>C)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6799

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL S111fs (c.332del)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6816

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL S65L (c.194C>T)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Predisposition3accepted
EID6791

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL S65W (c.194C>G)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Predisposition3accepted
EID6789

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL S80fs (c.239_245del)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6798

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic
VHL S80fs (c.239del)1
(predisposing)Von Hippel-Lindau DiseaseUNRESOLVEDPredisposingCSupports Uncertain Significance3submitted
EID6797

A retrospective cohort study included all the VHL patients diagnosed at Peking University First Hospital (Beijing, China) prior to June 1 2016. A total of 291 patients from 115 different families were… (full text at CIViC)

PMID 28388566 · Peng et al., 2017 · Open in CIViC

civic