Publication
Attainment of a Long-term Favorable Outcome by Sunitinib Treatment for Pancreatic Neuroendocrine Tumor and Renal Cell Carcinoma Associated with von Hippel-Lindau Disease.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
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Data not yet available
Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneVHLcivic_curation1.00
- variantVHL N78S (c.233A>G)civic_curation1.00
Curated evidence
Evidence citing this paper (3)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26984080
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| VHL N78S (c.233A>G)3 | ||||||||
| (predisposing) | Von Hippel-Lindau DiseaseUNRESOLVED | Predisposing | C | Supports Uncertain Significance | 2 | accepted | EID6289A male patient with Type 1 VHL disease presented with vision loss and retinal angiomatosis in the right eye at 19Y, left retinal angiomatosis at 23Y as well as CNS hemangioblastomas, neuroendocrine t… (full text at CIViC) PMID 26984080 · Kobayashi et al., 2016 · Open in CIViC | civic |
| 〃 | Von Hippel-Lindau DiseaseUNRESOLVED | Predisposing | C | Supports Uncertain Significance | 2 | rejected | EID6545A male patient with Type 1 VHL disease presented with vision loss and retinal angiomatosis in the right eye at 19Y, left retinal angiomatosis at 23Y and CNS hemangioblastomas and renal tumors at 25Y.… (full text at CIViC) PMID 26984080 · Kobayashi et al., 2016 · Open in CIViC | civic |
| Sunitinib | Von Hippel-Lindau DiseaseUNRESOLVED | Predictive | C | Supports Sensitivity Response | 2 | submitted | EID6429A male patient with Type 1 VHL disease, clinical family history of VHL, and a history of retinal and CNS hemangioblastomas, presented with neuroendocrine tumor of the pancreas with metastases to the l… (full text at CIViC) PMID 26984080 · Kobayashi et al., 2016 · Open in CIViC | civic |