Publication
Loss of the tumor suppressor SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type (SCCOHT).
Authors not recorded
Rare Dis2014PMID 26942101PMC4755243stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (2)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 2
- geneSMARCA4civic_curation1.00
- variantSMARCA4 INACTIVATING MUTATIONcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26942101
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| SMARCA4 INACTIVATING MUTATION1 | ||||||||
| (diagnostic) | Small-cell Carcinoma Of The Ovary Of Hypercalcemic TypeUNRESOLVED | Diagnostic | B | Supports Positive | 3 | accepted | EID8065Performed Sanger sequencing and immunohistochemistry of SMARCA4 in 12 SCCOHT (Small cell carcinoma of the ovary, hypercalcemic type) tumors. When complementing this data with data previous data from o… (full text at CIViC) PMID 26942101 · Ramos et al., 2014 · Open in CIViC | civic |