Publication
Epiregulin is required for lung tumor promotion in a murine two-stage carcinogenesis model.
Authors not recorded
Mol Carcinog2017PMID 26894620PMC5575741stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerLung Adenocarcinomacivic_curation1.00
- geneEREGcivic_curation1.00
- variantEREG EXPRESSIONcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 26894620
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| EREG EXPRESSION1 | ||||||||
| (prognostic) | Lung Adenocarcinoma | Prognostic | E | Supports Poor Outcome | 2 | accepted | EID1055Study reporting an in-vivo two-stage initiation/promotion model, testing the hypothesis that Ereg deficiency would reduce lung tumor promotion in mice. Cancerogenesis with chemical initiators/promoter… (full text at CIViC) PMID 26894620 · Bauer et al., 2017 · Open in CIViC | civic |