Publication
MEN1 mutations in Hürthle cell (oncocytic) thyroid carcinoma.
Authors not recorded
J Clin Endocrinol Metab2015PMID 25625803PMC4399284stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerThyroid Gland Oncocytic Carcinomacivic_curation1.00
- geneMEN1civic_curation1.00
- variantMEN1 FRAMESHIFT TRUNCATIONcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25625803
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| MEN1 FRAMESHIFT TRUNCATION1 | ||||||||
| (diagnostic) | Thyroid Gland Oncocytic CarcinomaALIAS | Diagnostic | C | Supports Positive | 2 | accepted | EID1695Two patients diagnosed with oncocytic thyroid carcinoma (hurthle cell thyroid carcinoma) were evaluated for MEN1 mutations. One tumor showed 592-end deletion of MEN1 and the other showed a 521 frames… (full text at CIViC) PMID 25625803 · Kasaian et al., 2015 · Open in CIViC | civic |