Publication
Diagnostic and prognostic TERT promoter mutations in thyroid fine-needle aspiration biopsy.
Authors not recorded
Endocr Relat Cancer2014PMID 25121551PMC4175020stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerMalignant Thyroid Gland Neoplasmcivic_curation1.00
- geneTERTcivic_curation1.00
- variantTERT C228Tcivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 25121551
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| TERT C228T1 | ||||||||
| (diagnostic) | Malignant Thyroid Gland Neoplasm | Diagnostic | B | Supports Positive | 3 | accepted | EID1646In 308 thyroid fine-needle aspiration biopsies, 0 of the 179 benign tumors displayed either the C228T or the C250T TERT promoter mutation; however, 9 of the 129 differentiated thyroid cancers had eith… (full text at CIViC) PMID 25121551 · Liu et al., 2014 · Open in CIViC | civic |