Publication
Distribution and levels of cell surface expression of CD33 and CD123 in acute myeloid leukemia.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (5)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 5
- cancerAcute Myeloid Leukemiacivic_curation1.00
- drugAnti-CD123civic_curation1.00
- drugAnti-CD33civic_curation1.00
- geneNPM1civic_curation1.00
- variantNPM1 EXON 11 MUTATIONcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 24927407
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| NPM1 EXON 11 MUTATION2 | ||||||||
| Anti-CD33 | Acute Myeloid LeukemiaCURATED_BROADER | Predictive | E | Supports Sensitivity Response | 2 | accepted | EID151CD33 expression was significantly increased in patients with NPM1 mutation with or without FLT3-ITD, indicating these patients may respond to anti-CD33 therapy. PMID 24927407 · Ehninger et al., 2014 · Open in CIViC | civic |
| Anti-CD123 + Anti-CD33Combination | Acute Myeloid LeukemiaCURATED_BROADER | Predictive | E | Supports Sensitivity Response | 2 | accepted | EID150CD33 and CD123 expression was significantly increased in patients with NPM1 mutation with FLT3-ITD, indicating these patients may respond to combined anti-CD33 and anti-CD123 therapy. PMID 24927407 · Ehninger et al., 2014 · Open in CIViC | civic |