Publication
Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers.
Authors not recorded
Clin Cancer Res2012PMID 23014527PMC3500422stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerMalignant Lung Neoplasmcivic_curation1.00
- geneKRAScivic_curation1.00
- variantKRAS G12Ccivic_curation1.00
- variantKRAS G12Dcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 23014527
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| KRAS G12C1 | ||||||||
| (diagnostic) | Malignant Lung Neoplasm | Diagnostic | B | Supports Positive | 2 | accepted | EID227KRAS G12C occur more frequently in women than men. PMID 23014527 · Dogan et al., 2012 · Open in CIViC | civic |
| KRAS G12D1 | ||||||||
| (diagnostic) | Malignant Lung Neoplasm | Diagnostic | B | Supports Positive | 3 | accepted | EID228KRAS G12D mutation occurs in never smokers significantly more often than in smokers. PMID 23014527 · Dogan et al., 2012 · Open in CIViC | civic |