Lohr et al. PNAS 2012 — PMID 22343534

Abstract

Abstract (excerpt)

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Linked entities

Linked entities (1)

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Validated 1

cancerDiffuse Large B-Cell Lymphoma Unclassifiablecbioportal_study1.00

Curated evidence

Evidence citing this paper (4)

civicCuratedShowing 1–4 of 4 evidence items · levels, directions and significance as curated at the source; each row links to its CIViC record.

Therapy	Cancer	Type	Level	Direction · significance	Rating (1–5)	Status	Evidence	Source
ACTB Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11906 This study performed exome sequencing on 55 DLBCL tumor samples and identified several significantly mutated genes including ACTB. PMID 22343534 · Lohr et al., 2012 · Open in CIViC	civic
BRAF Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11937 This study performed exome sequencing on 55 DLBCL tumor samples and identified several significantly mutated genes including BRAF. PMID 22343534 · Lohr et al., 2012 · Open in CIViC	civic
KRAS Mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11960 This study performed exome sequencing on 55 DLBCL tumor samples and identified several significantly mutated genes including KRAS. PMID 22343534 · Lohr et al., 2012 · Open in CIViC	civic
P2RY8 mutation1
(oncogenic)	Diffuse Large B-Cell LymphomaCURATED_BROADER	Oncogenic	E	Supports Oncogenicity	4	submitted	EID11973 This study performed exome sequencing on 55 DLBCL tumor samples and identified several significantly mutated genes including. PMID 22343534 · Lohr et al., 2012 · Open in CIViC	civic