Publication
Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer.
Authors not recorded
JAMA2012PMID 22274685PMC3727895stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (5)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 5
- cancerOvarian Carcinomacivic_curation1.00
- geneBRCA1civic_curation1.00
- geneBRCA2civic_curation1.00
- variantBRCA1 Mutationcivic_curation1.00
- variantBRCA2 Mutationcivic_curation1.00
Curated evidence
Evidence citing this paper (2)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 22274685
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| BRCA1 Mutation1 | ||||||||
| (prognostic) | Ovarian CarcinomaALIAS | Prognostic | B | Supports Better Outcome | 3 | accepted | EID464In patients with invasive epithelial ovarian cancer, those with mutations in BRCA1 had better five-year overall survival. PMID 22274685 · Bolton et al., 2012 · Open in CIViC | civic |
| BRCA2 Mutation1 | ||||||||
| (prognostic) | Ovarian CarcinomaALIAS | Prognostic | B | Supports Better Outcome | 3 | accepted | EID465In patients with invasive epithelial ovarian cancer, those with mutations in BRCA2 had better five-year overall survival. PMID 22274685 · Bolton et al., 2012 · Open in CIViC | civic |