Publication
When is prophylactic thyroidectomy indicated for patients with the RET codon 609 mutation?
Authors not recorded
Ann Surg Oncol2009PMID 19472011stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (3)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 3
- cancerThyroid Gland Medullary Carcinomacivic_curation1.00
- geneRETcivic_curation1.00
- variantRET C609Ycivic_curation1.00
Curated evidence
Evidence citing this paper (1)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 19472011
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| RET C609Y1 | ||||||||
| (predisposing) | Thyroid Gland Medullary CarcinomaALIAS | Predisposing | B | Supports Predisposition | 4 | accepted | EID2913Study of a family with three generations of history indicating co-segregation of RET C609Y and multiple endocrine neoplasia type 2A, many of whom exhibited medullary thyroid cancers specifically. 22 … (full text at CIViC) PMID 19472011 · Calva et al., 2009 · Open in CIViC | civic |