Publication
Cyclin D1 in non-small cell lung cancer: a key driver of malignant transformation.
Authors not recorded
Lung Cancer2007PMID 17070615stubpubmedProvenance
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
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Linked entities
Linked entities (4)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 4
- cancerLung Non-Small Cell Carcinomacivic_curation1.00
- geneCCND1civic_curation1.00
- variantCCND1 Amplificationcivic_curation1.00
- variantCCND1 Expressioncivic_curation1.00
Curated evidence
Evidence citing this paper (3)
civicProvenance
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 17070615
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| CCND1 Amplification1 | ||||||||
| (prognostic) | Lung Non-Small Cell CarcinomaCURATED_BROADER | Prognostic | B | Supports Poor Outcome | 3 | accepted | EID354Inceased copy number of CCND1 is associated with poorer overall survival. PMID 17070615 · Gautschi et al., 2007 · Open in CIViC | civic |
| CCND1 Expression2 | ||||||||
| (prognostic) | Lung Non-Small Cell CarcinomaCURATED_BROADER | Prognostic | B | Does Not Support Poor Outcome | 3 | accepted | EID342Three studies have found no significant survival impact for CCND1 in lung cancer. PMID 17070615 · Gautschi et al., 2007 · Open in CIViC | civic |
| 〃 | Lung Non-Small Cell CarcinomaCURATED_BROADER | Prognostic | B | Supports Poor Outcome | 3 | accepted | EID355Three studies have associated CCND1 expression with poorer survival. PMID 17070615 · Gautschi et al., 2007 · Open in CIViC | civic |