Publication
Prevalence of von Hippel-Lindau gene mutations in sporadic renal cell carcinoma: results from The Netherlands cohort study.
Authors not recorded
- Source
- PubMed
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Run
- ING-CIVIC-20260908-000001
Abstract
Abstract (excerpt)
Only the opening of the abstract is shown; abstract text may carry publisher copyright.
Data not yet available
Linked entities
Linked entities (6)
How each link was made (MeSH, dictionary, registry reference, curation…) and whether it has been validated. Candidate links are not counted in entity statistics.
Validated 6
- cancerChromophobe Renal Cell Carcinomacivic_curation1.00
- cancerClear Cell Renal Cell Carcinomacivic_curation1.00
- geneVHLcivic_curation1.00
- variantVHL M1? (c.1-1_20del21)civic_curation1.00
- variantVHL M1FS (c.1_17del17)civic_curation1.00
- variantVHL Y98FS (c.291_310del20)civic_curation1.00
Curated evidence
Evidence citing this paper (3)
- Source
- CIViC — Clinical Interpretation of Variants in Cancer
- Dataset
- CIViC evidence items
- Version
- civic-2026-09-08
- Retrieved
- Sep 8, 2026
- Layer
- normalized (units and labels harmonized; values unchanged)
- Evidence
- expert curation
- License
- CC0 1.0
- PMID
- 15932632
- Run
- ING-CIVIC-20260908-000001
| Therapy | Cancer | Type | Level | Direction · significance | Rating (1–5) | Status | Evidence | Source |
|---|---|---|---|---|---|---|---|---|
| VHL M1FS (c.1_17del17)1 | ||||||||
| (oncogenic) | Chromophobe Renal Cell Carcinoma | Oncogenic | C | Supports Oncogenicity | 1 | accepted | EID1945This somatic mutation was detected in two samples from a single patient with chromophobe renal cell carcinoma (a 74 year old male). The tumor also harbored a silent T157= (c.471T>A) somatic variant. PMID 15932632 · van Houwelingen et al., 2005 · Open in CIViC | civic |
| VHL M1? (c.1-1_20del21)1 | ||||||||
| (oncogenic) | Clear Cell Renal Cell Carcinoma | Oncogenic | C | Supports Oncogenicity | 1 | accepted | EID1946This variant was detected in a single case with clear-cell renal cell carcinoma. The tumor had two somatic variants (c.1-1_20del21 and c.291_310del20). Either of these variants is predicted to be quit… (full text at CIViC) PMID 15932632 · van Houwelingen et al., 2005 · Open in CIViC | civic |
| VHL Y98FS (c.291_310del20)1 | ||||||||
| (oncogenic) | Clear Cell Renal Cell Carcinoma | Oncogenic | C | Supports Oncogenicity | 1 | accepted | EID1951This variant was detected in a single case with clear-cell renal cell carcinoma. The tumor had two somatic variants (c.1-1_20del21 and c.291_310del20). Either of these variants is predicted to be quit… (full text at CIViC) PMID 15932632 · van Houwelingen et al., 2005 · Open in CIViC | civic |