Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

RECRUITING

Identifier: CI-TRIAL-00117364
Entity page: /trial/NCT07321912 ↗
Edges: 10

Neighbours: 2 cancers8 drugs
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma condition of …CONDITION_OFderived2 of 2
← condition of	Ewing Sarcoma registry condition “Ewing Sarcoma” mapped ONTOLOGY_EXACT	—	—	Ewing Sarcoma	1	Observed	clinicaltrials	graph →
← condition of	Osteosarcoma registry condition “Osteosarcoma” mapped ONTOLOGY_EXACT	—	—

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma intervention of …INTERVENTION_OFderived8 of 8
← intervention of	Cisplatinsmall molecule registry intervention “Cisplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cyclophosphamidesmall molecule registry intervention “Cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Doxorubicinsmall molecule registry intervention “Doxorubicin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Etoposidesmall molecule registry intervention “Etoposide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ifosfamidesmall molecule registry intervention “Ifosfamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Methotrexatesmall molecule registry intervention “Methotrexate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Topotecansmall molecule registry intervention “Topotecan” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vincristinesmall molecule registry intervention “Vincristine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma intervention of …INTERVENTION_OFderived8 of 8

← intervention of

Cisplatinsmall molecule

registry intervention “Cisplatin” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Cyclophosphamidesmall molecule

registry intervention “Cyclophosphamide” (DRUG) mapped ALIAS