Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial

NOT YET RECRUITING

Identifier: CI-TRIAL-00114332
Entity page: /trial/NCT07220187 ↗
Edges: 8

Neighbours: 2 cancers6 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial condition of …CONDITION_OFderived2 of 2
← condition of	Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma registry condition “Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma” mapped ONTOLOGY_EXACT	—	—	Transformed Chronic Lymphocytic Leukemia to Diffuse Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
condition of

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial intervention of …INTERVENTION_OFderived6 of 6
← intervention of	Cyclophosphamidesmall molecule registry intervention “Cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Doxorubicinsmall molecule registry intervention “Doxorubicin Hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pirtobrutinibsmall molecule registry intervention “Pirtobrutinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Prednisonesmall molecule registry intervention “Prednisone” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Rituximabmonoclonal antibody registry intervention “Rituximab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vincristinesmall molecule registry intervention “Vincristine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Adding Pirtobrutinib to the Usual Treatment for People With Newly Diagnosed Richter Transformation, The PIRAMID Trial intervention of …INTERVENTION_OFderived6 of 6

← intervention of

Cyclophosphamidesmall molecule

registry intervention “Cyclophosphamide” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Doxorubicinsmall molecule

registry intervention “Doxorubicin Hydrochloride” (DRUG) mapped ALIAS

—