Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study

RECRUITING

Identifier: CI-TRIAL-00106680
Entity page: /trial/NCT06769126 ↗
Edges: 8

Neighbours: 5 cancers3 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study condition of …CONDITION_OFderived5 of 5
← condition of	Lung Small Cell Carcinoma registry condition “Extensive Stage Lung Small Cell Carcinoma” mapped CURATED_BROADER	—	—	Lung Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Lung Small Cell Carcinoma, A Subtype registry condition “Lung Small Cell Carcinoma, A Subtype” mapped ONTOLOGY_EXACT

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Durvalumabmonoclonal antibody registry intervention “Durvalumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Etoposidesmall molecule registry intervention “Etoposide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Platinum Compound registry intervention “Platinum Compound” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Using Biomarker Tests to Select and Test New, Personalized Treatments for Extensive Stage Small Cell Lung Cancer, PRISM Study intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Durvalumabmonoclonal antibody

registry intervention “Durvalumab” (BIOLOGICAL) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Etoposidesmall molecule

registry intervention “Etoposide” (DRUG) mapped ALIAS

—