Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation

RECRUITING

Identifier: CI-TRIAL-00080092
Entity page: /trial/NCT06316960 ↗
Edges: 8

Neighbours: 3 cancers5 drugs
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation condition of …CONDITION_OFderived3 of 3
← condition of	Acute Myeloid Leukemia registry condition “Refractory AML” mapped CURATED_BROADER	—	—	Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
← condition of	Childhood Acute Myeloid Leukemia registry condition “AML, Childhood” mapped CURATED_BROADER	—

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation intervention of …INTERVENTION_OFderived5 of 5
← intervention of	Avapritinibsmall molecule registry intervention “Avapritinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Azacitidinesmall molecule registry intervention “Azacitidine Injection” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cytarabinesmall molecule registry intervention “Cytarabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Decitabinesmall molecule registry intervention “Decitabine Injection” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Idarubicinsmall molecule registry intervention “Idarubicin Hydrochloride” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation intervention of …INTERVENTION_OFderived5 of 5

← intervention of

Avapritinibsmall molecule

registry intervention “Avapritinib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Azacitidinesmall molecule

registry intervention “Azacitidine Injection” (DRUG) mapped ALIAS