Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00111030
Entity page: /trial/NCT05319873 ↗
Edges: 10

Neighbours: 2 cancers7 drugs
Drawn: 9 of 9 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer condition of …CONDITION_OFderived3 of 3
← condition of	HER2-Positive Breast Carcinoma registry condition “Locally Advanced HER2-Positive Breast Carcinoma” mapped CURATED_BROADER	—	—	HER2-Positive Breast Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	HER2-Positive Breast Carcinoma registry condition “Metastatic HER2-Positive Breast Carcinoma” mapped CURATED_BROADER

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer intervention of …INTERVENTION_OFderived7 of 7
← intervention of	Carboplatinsmall molecule registry intervention “Carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Docetaxelsmall molecule registry intervention “Docetaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Fulvestrantsmall molecule registry intervention “Fulvestrant” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pertuzumabmonoclonal antibody registry intervention “Pertuzumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ribociclibsmall molecule registry intervention “Ribociclib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “Trastuzumab” (BIOLOGICAL) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Tucatinibsmall molecule registry intervention “Tucatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Ribociclib, Tucatinib, and Trastuzumab for the Treatment of HER2 Positive Breast Cancer intervention of …INTERVENTION_OFderived7 of 7

← intervention of

Carboplatinsmall molecule

registry intervention “Carboplatin” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Docetaxelsmall molecule

registry intervention “Docetaxel” (DRUG) mapped ALIAS