Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00121455
Entity page: /trial/NCT05113251 ↗
Edges: 7

Neighbours: 2 cancers5 drugs
Drawn: 7 of 7 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer condition of …CONDITION_OFderived2 of 2
← condition of	Breast Neoplasm registry condition “Breast Neoplasms” mapped ONTOLOGY_EXACT	—	—	Breast Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Malignant Breast Neoplasm registry condition “Breast Cancer” mapped CURATED_EXACT	—	—

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer intervention of …INTERVENTION_OFderived5 of 5
← intervention of	Cyclophosphamidesmall molecule registry intervention “cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Doxorubicinsmall molecule registry intervention “Doxorubicin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Paclitaxelsmall molecule registry intervention “Paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pertuzumabmonoclonal antibody registry intervention “Pertuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Trastuzumabmonoclonal antibody registry intervention “Trastuzumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Trastuzumab Deruxtecan (T-DXd) Alone or in Sequence With THP, Versus Standard Treatment (ddAC-THP), in HER2-positive Early Breast Cancer intervention of …INTERVENTION_OFderived5 of 5

← intervention of

Cyclophosphamidesmall molecule

registry intervention “cyclophosphamide” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Doxorubicinsmall molecule

registry intervention “Doxorubicin” (DRUG) mapped ALIAS

—