The Drug Rediscovery Protocol (DRUP Trial)

RECRUITING

Identifier: CI-TRIAL-00073242
Entity page: /trial/NCT02925234 ↗
Edges: 37

Neighbours: 2 cancers15 drugs
Drawn: 17 of 17 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
The Drug Rediscovery Protocol (DRUP Trial) condition of …CONDITION_OFderived4 of 4
← condition of	Malignant Neoplasm registry condition “Cancer” mapped ALIAS	—	—	Malignant Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Neoplasm registry condition “Neoplasia” mapped ALIAS	—	—

The Drug Rediscovery Protocol (DRUP Trial) intervention of …INTERVENTION_OFderived15 of 33show all (up to 200)
← intervention of	Abemaciclibsmall molecule registry intervention “Abemaciclib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Afatinibsmall molecule registry intervention “Afatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Alectinibsmall molecule registry intervention “Alectinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Alpelisibsmall molecule registry intervention “Alpelisib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Axitinibsmall molecule registry intervention “Axitinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cabozantinibsmall molecule registry intervention “Cabozantinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Crizotinibsmall molecule registry intervention “Crizotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dabrafenibsmall molecule registry intervention “Dabrafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dabrafenib/Trametinib Regimen registry intervention “Dabrafenib and trametinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Durvalumabmonoclonal antibody registry intervention “Durvalumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Entrectinibsmall molecule registry intervention “Entrectinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Erdafitinibsmall molecule registry intervention “Erdafitinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Erlotinibsmall molecule registry intervention “Erlotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Ipilimumab/Nivolumab Regimen registry intervention “Ipilimumab and nivolumab” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Lenvatinibsmall molecule registry intervention “Lenvatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Radial view

Every edge, grouped by relationship

Paths