An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies

TERMINATED

Identifier: CI-TRIAL-00044722
Entity page: /trial/NCT02265510 ↗
Edges: 10

Neighbours: 2 cancers8 drugs
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies condition of …CONDITION_OFderived2 of 2
← condition of	Malignant Neoplasm registry condition “Metastatic Cancer” mapped CURATED_BROADER	—	—	Malignant Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Solid Neoplasm registry condition “Solid Tumors” mapped CURATED_BROADER	—	—

An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies intervention of …INTERVENTION_OFderived8 of 8
← intervention of	Azacitidinesmall molecule registry intervention “azacitidine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Bortezomibsmall molecule registry intervention “bortezomib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carfilzomibother registry intervention “Carfilzomib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Dexamethasonesmall molecule registry intervention “dexamethasone” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Gemcitabinesmall molecule registry intervention “gemcitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Lenalidomidesmall molecule registry intervention “lenalidomide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Nab-paclitaxel registry intervention “nab-paclitaxel” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pomalidomidesmall molecule registry intervention “pomalidomide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

An Open-Label Study of a Novel JAK-inhibitor, INCB052793, Given to Patients With Advanced Malignancies intervention of …INTERVENTION_OFderived8 of 8

← intervention of

Azacitidinesmall molecule

registry intervention “azacitidine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Bortezomibsmall molecule

registry intervention “bortezomib” (DRUG) mapped ALIAS