Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors

ACTIVE NOT RECRUITING

Identifier: CI-TRIAL-00125029
Entity page: /trial/NCT02114229 ↗
Edges: 10

Neighbours: 2 cancers8 drugs
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors condition of …CONDITION_OFderived2 of 2
← condition of	Atypical Teratoid/Rhabdoid Tumor registry condition “Atypical Teratoid Rhabdoid Tumor” mapped ONTOLOGY_EXACT	—	—	Atypical Teratoid/Rhabdoid Tumor	1	Observed	clinicaltrials	graph →
← condition of	Rhabdoid Tumor registry condition “Malignant Rhabdoid Tumor” mapped PROBABILISTIC	—

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors intervention of …INTERVENTION_OFderived8 of 8
← intervention of	Alisertibsmall molecule registry intervention “alisertib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Carboplatinsmall molecule registry intervention “carboplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cisplatinsmall molecule registry intervention “cisplatin” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Cyclophosphamidesmall molecule registry intervention “cyclophosphamide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Etoposidesmall molecule registry intervention “etoposide” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Methotrexatesmall molecule registry intervention “methotrexate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Topotecansmall molecule registry intervention “topotecan” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vincristinesmall molecule registry intervention “vincristine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Phase 2 Study of Alisertib Therapy for Rhabdoid Tumors intervention of …INTERVENTION_OFderived8 of 8

← intervention of

Alisertibsmall molecule

registry intervention “alisertib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Carboplatinsmall molecule

registry intervention “carboplatin” (DRUG) mapped ALIAS