Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis

COMPLETED

Identifier: CI-TRIAL-00041562
Entity page: /trial/NCT01783756 ↗
Edges: 7

Neighbours: 3 cancers3 drugs
Drawn: 6 of 6 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis condition of …CONDITION_OFderived4 of 4
← condition of	HER2-Positive Breast Carcinoma registry condition “HER2-positive Breast Cancer” mapped ALIAS	—	—	HER2-Positive Breast Carcinoma	1	Observed	clinicaltrials	graph →
← condition of	Male Breast Carcinoma registry condition “Male Breast Cancer” mapped ALIAS

Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis intervention of …INTERVENTION_OFderived3 of 3
← intervention of	Capecitabinesmall molecule registry intervention “capecitabine” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Everolimussmall molecule registry intervention “everolimus” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Lapatinibsmall molecule registry intervention “lapatinib ditosylate” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Phase 1b/2 Trial Using Lapatinib, Everolimus and Capecitabine for Treatment of HER-2 Positive Breast Cancer With CNS Metastasis intervention of …INTERVENTION_OFderived3 of 3

← intervention of

Capecitabinesmall molecule

registry intervention “capecitabine” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Everolimussmall molecule

registry intervention “everolimus” (DRUG) mapped ALIAS

—