Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies.

COMPLETED

Identifier: CI-TRIAL-00051285
Entity page: /trial/NCT01636908 ↗
Edges: 10

Neighbours: 2 cancers8 drugs
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. condition of …CONDITION_OFderived2 of 2
← condition of	Malignant Neoplasm registry condition “Cancer” mapped ALIAS	—	—	Malignant Neoplasm	1	Observed	clinicaltrials	graph →
← condition of	Solid Neoplasm registry condition “Advanced Solid Tumors” mapped CURATED_BROADER	—	—

Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. intervention of …INTERVENTION_OFderived8 of 8
← intervention of	Dasatinibsmall molecule registry intervention “Dasatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Erlotinibsmall molecule registry intervention “Erlotinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Everolimussmall molecule registry intervention “Everolimus” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Lapatinibsmall molecule registry intervention “Lapatinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Pazopanibsmall molecule registry intervention “Pazopanib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Sorafenibsmall molecule registry intervention “Sorafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Sunitinibsmall molecule registry intervention “Sunitinib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →
← intervention of	Vemurafenibsmall molecule registry intervention “Vemurafenib” (DRUG) mapped ALIAS	—	—	not mapped	1	Observed	clinicaltrials	graph →

Determination of Intratumoral Concentrations of Kinase Inhibitors in Patients With Advanced Solid Malignancies. intervention of …INTERVENTION_OFderived8 of 8

← intervention of

Dasatinibsmall molecule

registry intervention “Dasatinib” (DRUG) mapped ALIAS

—

not mapped

Observed

clinicaltrials

graph →

← intervention of

Erlotinibsmall molecule

registry intervention “Erlotinib” (DRUG) mapped ALIAS

—