TIMP1

TIMP metallopeptidase inhibitor 1

Identifier: CI-GENE-00035204
Entity page: /gene/TIMP1 ↗
Edges: 4

Neighbours: 1 cancers2 variants
Drawn: 3 of 3 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
TIMP1 associated with …ASSOCIATED_WITH2 of 2
→ associated with	Malignant Breast Neoplasmcancer_family	supports	B	Malignant Breast Neoplasm	1	Curated	civic	graph →
→ associated with	Malignant Breast Neoplasmcancer_family	supports	D

TIMP1 has variant …HAS_VARIANTderived2 of 2
→ has variant	Overexpressionexpression 2 accepted CIViC evidence items	—	—	Malignant Breast Neoplasm	2	Curated	civic	graph →
→ has variant	NM_003254.3(TIMP1):c.575G>A (p.Arg192Gln)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

TIMP1 has variant …HAS_VARIANTderived2 of 2

→ has variant

Overexpressionexpression

2 accepted CIViC evidence items

—

Malignant Breast Neoplasm

Curated

civic

graph →

→ has variant

NM_003254.3(TIMP1):c.575G>A (p.Arg192Gln)SNV

no accepted CIViC evidence item (variant record only)