TACC3

transforming acidic coiled-coil containing protein 3

Identifier: CI-GENE-00034443
Entity page: /gene/TACC3 ↗
Edges: 12

Neighbours: 4 cancers7 variants
Drawn: 11 of 11 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
TACC3 associated with …ASSOCIATED_WITH5 of 5
→ associated with	Malignant Neoplasmcancer_family	supports	B	Malignant Neoplasm	1	Curated	civic	graph →
→ associated with	Glioblastomasubtype	supports	C

TACC3 has variant …HAS_VARIANTderived7 of 7
→ has variant	Fusionfusion 5 accepted CIViC evidence items	—	—	Malignant Neoplasm,Glioblastoma,Transitional Cell Carcinoma	5	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	Cholangiocarcinoma	1	Curated	civic	graph →
→ has variant	NM_006342.3(TACC3):c.109C>G (p.Arg37Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_006342.3(TACC3):c.1558C>G (p.Leu520Val)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_006342.3(TACC3):c.1605C>T (p.Gly535=)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_006342.3(TACC3):c.254A>G (p.Asp85Gly)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_006342.3(TACC3):c.98C>A (p.Ser33Ter)SNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

TACC3 has variant …HAS_VARIANTderived7 of 7

→ has variant

Fusionfusion

5 accepted CIViC evidence items

—

Malignant Neoplasm,Glioblastoma,Transitional Cell Carcinoma

Curated

civic

graph →

→ has variant

Fusionfusion

1 accepted CIViC evidence items