DLL3

delta like canonical Notch ligand 3

Identifier: CI-GENE-00043469
Entity page: /gene/DLL3 ↗
Edges: 4

Neighbours: 2 variants2 drugs
Drawn: 4 of 4 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
DLL3 targets …TARGETS2 of 2
← targets	Tarlatamabmonoclonal_antibody	—	BINDING AGENT	—	1	Curated	chembl	graph →
← targets	Rovalpituzumab Tesirineadc	—	BINDING AGENT	—	1	Curated	chembl

DLL3 has variant …HAS_VARIANTderived2 of 2
→ has variant	Expressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	NM_203486.3(DLL3):c.1759-2_1762deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

DLL3 has variant …HAS_VARIANTderived2 of 2

→ has variant

Expressionexpression

no accepted CIViC evidence item (variant record only)

—

not mapped

Observed

civic

graph →

→ has variant

NM_203486.3(DLL3):c.1759-2_1762deldeletion

no accepted CIViC evidence item (variant record only)