CRLF2

cytokine receptor like factor 2

Identifier: CI-GENE-00042241
Entity page: /gene/CRLF2 ↗
Edges: 11

Neighbours: 2 cancers8 variants
Drawn: 10 of 10 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
CRLF2 associated with …ASSOCIATED_WITH3 of 3
→ associated with	Adult B Acute Lymphoblastic Leukemiahematologic_malignancy	supports	B	Adult B Acute Lymphoblastic Leukemia	1	Curated	civic	graph →
→ associated with	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Likehematologic_malignancy	supports

CRLF2 has variant …HAS_VARIANTderived8 of 8
→ has variant	Fusionfusion 5 accepted CIViC evidence items	—	—	Adult B Acute Lymphoblastic Leukemia,B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like	5	Curated	civic	graph →
→ has variant	Fusionfusion 1 accepted CIViC evidence items	—	—	B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like	1	Curated	civic	graph →
→ has variant	F232CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	F232CSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	G24RSNV no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Overexpressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	Rearrangementstructural no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →
→ has variant	V2deldeletion no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

CRLF2 has variant …HAS_VARIANTderived8 of 8

→ has variant

Fusionfusion

5 accepted CIViC evidence items

—

Adult B Acute Lymphoblastic Leukemia,B Lymphoblastic Leukemia/Lymphoma, BCR-ABL1-Like

Curated

civic

graph →

→ has variant

Fusionfusion

1 accepted CIViC evidence items