AREG

amphiregulin

Identifier: CI-GENE-00011153
Entity page: /gene/AREG ↗
Edges: 6

Neighbours: 3 cancers2 variants
Drawn: 5 of 5 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
AREG associated with …ASSOCIATED_WITH4 of 4
→ associated with	Malignant Colorectal Neoplasmsubtype 2 source records aggregated	supports	B	Malignant Colorectal Neoplasm	2	Curated	civic	graph →
→ associated with	Head and Neck Squamous Cell Carcinomasubtype	supports

AREG has variant …HAS_VARIANTderived2 of 2
→ has variant	Expressionexpression 5 accepted CIViC evidence items	—	—	Head and Neck Squamous Cell Carcinoma,Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm	5	Curated	civic	graph →
→ has variant	overexpressionexpression no accepted CIViC evidence item (variant record only)	—	—	not mapped	0	Observed	civic	graph →

AREG has variant …HAS_VARIANTderived2 of 2

→ has variant

Expressionexpression

5 accepted CIViC evidence items

—

Head and Neck Squamous Cell Carcinoma,Lung Non-Small Cell Carcinoma,Malignant Colorectal Neoplasm

Curated

civic

graph →

→ has variant

overexpressionexpression

no accepted CIViC evidence item (variant record only)