Therapeutic Tumor Infiltrating Lymphocytes

Identifier: CI-DRUG-00000589
Entity page: /drug/therapeutic-tumor-infiltrating-lymphocytes ↗
Edges: 100

Neighbours: 15 cancers2 variants10 trials
Drawn: 27 of 27 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Therapeutic Tumor Infiltrating Lymphocytes predicts response to …PREDICTS_RESPONSE_TO2 of 2
← predicts response to	HLA-C COPY-NEUTRAL LOSS OF HETEROZYGOSITYloss_of_heterozygosity	resistance	C	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
← predicts response to	KRAS G12DSNV	sensitivity

Therapeutic Tumor Infiltrating Lymphocytes investigated for …INVESTIGATED_FOR1 of 1
→ investigated for	Malignant Colorectal Neoplasmsubtype 2 source records aggregated	supports	C	Malignant Colorectal Neoplasm	2	Curated	civic	graph →

Therapeutic Tumor Infiltrating Lymphocytes investigated for …INVESTIGATED_FOR1 of 1

→ investigated for

Malignant Colorectal Neoplasmsubtype

2 source records aggregated

supports

Malignant Colorectal Neoplasm

Curated

Therapeutic Tumor Infiltrating Lymphocytes investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 47show all (up to 200)
→ investigated in trials for	Melanoma 21 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Melanoma	21	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Breast Neoplasm 5 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Breast Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasm 5 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colorectal Neoplasmsubtype 4 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colorectal Neoplasm	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cutaneous Melanoma 3 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Cutaneous Melanoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Gastric Neoplasm 3 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Gastric Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Lung Neoplasm 3 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Lung Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Ovarian Neoplasm 3 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Ovarian Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 3 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Adult Solid Neoplasm 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Adult Solid Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Digestive System Neoplasm 2 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Digestive System Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Glioma 2 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Glioma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinoma 2 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Cervical Neoplasm 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Cervical Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colon Neoplasm 2 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colon Neoplasm	2	Observed	clinicaltrials	graph →

Therapeutic Tumor Infiltrating Lymphocytes studied in …STUDIED_INderived10 of 50show all (up to 200)
→ studied in	NCT05681780Phase 1 · recruiting Clinical Trial of CD40L-Augmented TIL for Patients With EGFR, ALK, ROS1 or HER2-Driven NSCLC · 50 trials list this drug (16 active)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04943913early Phase 1 · recruiting Study of GC101 TIL in Brain Glioma (Soochow2) · 50 trials list this drug (16 active)	—	—	Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04960072early Phase 1 · recruiting A Study of GC101 TIL in r/r Gastrointestinal Tumors (10hospital) · 50 trials list this drug (16 active)	—	—	Digestive System Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT04967833early Phase 1 · recruiting A Study of GC101 TIL in Advanced Solid Tumors (TR) · 50 trials list this drug (16 active)	—	—	Solid Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05087745early Phase 1 · recruiting A Clinical Study on TIL for the Treatment of Advanced Solid Tumors · 50 trials list this drug (16 active)	—	—	Solid Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07647068Phase 2 · not yet recruiting Autologous Tumor Infiltrating Lymphocytes With Interleukin-2 for the Treatment of Locally Advanced, Recurrent or Metastatic Gastrointestinal Stromal Tumors · 50 trials list this drug (16 active)	—	—	Gastrointestinal Stromal Tumor,Malignant Gastrointestinal Stromal Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07628894Phase 1 · not yet recruiting Circadian-Optimized Light Therapy for the Treatment of Patients With Advanced Melanoma Receiving Tumor-Infiltrating Lymphocyte Therapy · 50 trials list this drug (16 active)	—	—	Cutaneous Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03467516Phase 2 · active not recruiting Adoptive Transfer of Tumor Infiltrating Lymphocytes for Metastatic Uveal Melanoma · 50 trials list this drug (16 active)	—	—	Uveal Neoplasm,Uveal Melanoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03801083Phase 2 · active not recruiting Adoptive Transfer of Tumor Infiltrating Lymphocytes for Biliary Tract Cancers · 50 trials list this drug (16 active)	—	—	Malignant Biliary Tract Neoplasm,Cholangiocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03935893Phase 2 · active not recruiting Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers · 50 trials list this drug (16 active)	—	—	Malignant Mesothelioma,Sarcoma,Malignant Gastric Neoplasm+2	1	Observed	clinicaltrials	graph →

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