Immunomodulatory Oligonucleotide

Identifier: CI-DRUG-00000299
Entity page: /drug/immunomodulatory-oligonucleotide ↗
Edges: 61

Neighbours: 15 cancers1 variants10 trials
Drawn: 26 of 26 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Immunomodulatory Oligonucleotide predicts response to …PREDICTS_RESPONSE_TO1 of 1
← predicts response to	KRAS Mutationother	sensitivity	D	Malignant Colorectal Neoplasm	1	Curated	civic	graph →
Immunomodulatory Oligonucleotide investigated for …INVESTIGATED_FOR1 of 1
investigated for

Immunomodulatory Oligonucleotide investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 22show all (up to 200)
→ investigated in trials for	Malignant Colorectal Neoplasmsubtype 10 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colorectal Neoplasm	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Colorectal Neoplasm 3 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Colorectal Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Pancreatic Neoplasm 3 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Pancreatic Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Solid Neoplasm 3 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Solid Neoplasm	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Gastric Neoplasm 2 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Gastric Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Rectal Neoplasm 2 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Rectal Neoplasm	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Melanoma 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Melanoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Pancreatic Adenocarcinoma 2 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Pancreatic Adenocarcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Diffuse Large B-Cell Lymphoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Diffuse Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Gastric Neoplasm 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Intrahepatic Cholangiocarcinoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Intrahepatic Cholangiocarcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lung Non-Small Cell Carcinoma 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lung Non-Small Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Lymphoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Lymphoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Biliary Tract Neoplasm 1 trials (0 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Biliary Tract Neoplasm	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Malignant Colon Neoplasm 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Colon Neoplasm	1	Observed	clinicaltrials	graph →

Immunomodulatory Oligonucleotide investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 22show all (up to 200)

→ investigated in trials for

Malignant Colorectal Neoplasmsubtype

10 trials (4 active) · conditions mapped to this cancer only (no hierarchy roll-up)

—

Malignant Colorectal Neoplasm

Observed

Immunomodulatory Oligonucleotide studied in …STUDIED_INderived10 of 37show all (up to 200)
→ studied in	NCT07844187Phase 1/Phase 2 · not yet recruiting TQB2922 Injection Given Under the Skin With Chemotherapy as Initial Treatment for Colorectal Cancer That Has Spread · 37 trials list this drug (18 active)	—	—	Colorectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07069712Phase 2 · recruiting A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma · 37 trials list this drug (18 active)	—	—	Gastric Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07015242Phase 2 · recruiting A Study of the Efficacy and Safety of Lisocabtagene Maraleucel (Liso-cel) as First-Line Therapy in Adults With Transplant-Ineligible Primary Central Nervous System Lymphoma · 37 trials list this drug (18 active)	—	—	Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05253846Phase 2 · active not recruiting Short-course Radiotherapy Followed by Consolidation Chemotherapy. 2021-001206-29 · 37 trials list this drug (18 active)	—	—	Malignant Rectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07441369Phase 2 · enrolling by invitation Abemaciclib Combined With FOLFOX/FOLFIRI Regimen in Patients With Advanced Colorectal Liver Metastases Cancer · 37 trials list this drug (18 active)	—	—	not mapped	1	Observed	clinicaltrials	graph →
→ studied in	NCT07056777Phase 1/Phase 2 · recruiting Evaluation of the Preliminary Efficacy and Safety of DR30206 in Combination With Standard Therapy in Patients With Gastrointestinal Cancer · 37 trials list this drug (18 active)	—	—	Malignant Digestive System Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07621497Phase 2 · not yet recruiting FOLFOX8 Versus mFOLFOX6 With Bevacizumab or Cetuximab for First-Line Unresectable Metastatic Colorectal Cancer (Phase II) · 37 trials list this drug (18 active)	—	—	Malignant Colorectal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT06094140Phase 2 · active not recruiting NEO-adjuvant Chemo-immunotherapy in Pancreatic Cancer · 37 trials list this drug (18 active)	—	—	Malignant Pancreatic Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07412613Phase 3 · recruiting Neoadjuvant/Adjuvant AK104 in Microsatellite Instability-high or Mismatch Repair-deficient, Resectable Colon Cancer · 37 trials list this drug (18 active)	—	—	Malignant Colon Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07543744Phase 1 · recruiting A Comparative Study of Pharmacokinetics, Safety, and Immunogenicity of RPH-030 and Vectibix® in Patients With Metastatic Colorectal Cancer With Wild-type RAS as First-line Therapy in Combination With FOLFIRI · 37 trials list this drug (18 active)	—	—	Malignant Colorectal Neoplasm	1	Observed	clinicaltrials	graph →

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