Histrelin

other

Identifier: CI-DRUG-00000708
Entity page: /drug/histrelin ↗
Edges: 14

Neighbours: 7 cancers1 genes6 trials1 approvals
Drawn: 15 of 15 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Histrelin approved for …APPROVED_FOR2 of 1
→ approved for	Conventional Osteosarcomasubtype	supports	FDA ORIG	Conventional Osteosarcoma	1	Regulatory	openfda	graph →
→ approved for	Health Canada · CA · 2006Marketed in Canada as VANTAS (DIN 02278383) under ATC L02AE05 HISTRELIN. Indications are not published in the Drug Product Database — see the Health Canada Product Monograph.

Histrelin targets …TARGETS1 of 1
→ targets	GNRHR	—	AGONIST	—	1	Curated	chembl	graph →

Histrelin investigated for …INVESTIGATED_FOR2 of 2
→ investigated for	Neoplasmcancer_family	unknown	4	Neoplasm	1	Curated	chembl	graph →
→ investigated for	Prostate Neoplasmsubtype	unknown	4	Prostate Neoplasm	1	Curated	chembl	graph →

Histrelin investigated in trials for …INVESTIGATED_IN_TRIALSderived4 of 4
→ investigated in trials for	Malignant Prostate Neoplasm 5 trials (3 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Malignant Prostate Neoplasm	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Prostate Adenocarcinoma 4 trials (2 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Prostate Adenocarcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Castration-Resistant Prostate Carcinoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Castration-Resistant Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Castration-Sensitive Prostate Carcinoma 1 trials (1 active) · conditions mapped to this cancer only (no hierarchy roll-up)	—	—	Castration-Sensitive Prostate Carcinoma	1	Observed	clinicaltrials	graph →

Histrelin studied in …STUDIED_INderived6 of 6
→ studied in	NCT04513717Phase 3 · active not recruiting Two Studies for Patients With High Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a High Gene Risk Score, The PREDICT-RT Trial · 6 trials list this drug (4 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT05050084Phase 3 · active not recruiting Two Studies for Patients With Unfavorable Intermediate Risk Prostate Cancer Testing Less Intense Treatment for Patients With a Low Gene Risk Score and Testing a More Intense Treatment for Patients With a Higher Gene Risk Score, The Guidance Trial · 6 trials list this drug (4 active)	—	—	Prostate Adenocarcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06378866Phase 2 · recruiting Stereotactic Body Radiation Therapy Plus Immediate or Delayed Androgen Receptor Pathway Inhibitor and Androgen Deprivation Therapy or Salvage Radiation Therapy for the Treatment of Prostate Cancer, DIVINE Trial · 6 trials list this drug (4 active)	—	—	Malignant Prostate Neoplasm,Castration-Resistant Prostate Carcinoma,Castration-Sensitive Prostate Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03678025Phase 3 · recruiting Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer · 6 trials list this drug (4 active)	—	—	Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT02278185Phase 2 · completed Enzalutamide Versus Standard Androgen Deprivation Therapy for the Treatment Hormone Sensitive Prostate Cancer · 6 trials list this drug (4 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT01697384Phase 3 · completed Study to Evaluate Efficacy and Safety of Histrelin Subdermal Implant in Men With Advanced Prostate Cancer · 6 trials list this drug (4 active)	—	—	Prostate Adenocarcinoma,Malignant Prostate Neoplasm	1	Observed	clinicaltrials	graph →

Radial view

Every edge, grouped by relationship

Paths