Testicular Germ Cell Tumor

cancer family

Identifier: CI-CAN-00000362
Entity page: /cancer/testicular-germ-cell-tumor ↗
Edges: 252

Neighbours: 15 genes15 drugs10 trials
Drawn: 40 of 40 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Testicular Germ Cell Tumor altered in cohorts of …ALTERED_INderived15 of 98show all (up to 200)
← altered in cohorts of	KRAS 255 / 263 cases (97 %) · ssm · TCGA-TGCT	—	—	Testicular Germ Cell Tumor	1	Observed	gdc	graph →
← altered in cohorts of	ANO2 254 / 263 cases (97 %) · ssm · TCGA-TGCT

Testicular Germ Cell Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 39show all (up to 200)
→ investigated in trials for	Etoposidesmall molecule 22 trials (1 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	22	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 19 trials (1 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	19	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother 18 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	18	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 17 trials (2 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	17	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 16 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall molecule 13 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	13	Observed	clinicaltrials	graph →
→ investigated in trials for	Bleomycin 9 trials (1 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 9 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Thiotepasmall molecule 5 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Busulfansmall molecule 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Pegfilgrastimother 4 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Melphalansmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Oxaliplatinsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Alemtuzumabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Testicular Germ Cell Tumor	2	Observed	clinicaltrials	graph →

Testicular Germ Cell Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 39show all (up to 200)

→ investigated in trials for

Etoposidesmall molecule

22 trials (1 active) · roll-up of the cancer and its descendants

—

Testicular Germ Cell Tumor

Observed

Testicular Germ Cell Tumor studied in …STUDIED_INderived10 of 115show all (up to 200)
→ studied in	NCT07614620NA · recruiting Effect of Hypnosis in the Management of Anxiety and Chemo-induced Symptoms in Adolescents and Young Adults With Sarcoma or Germ Cell Tumor and in Young Women With Breast Cancer · condition mapped ALIAS · 115 trials mapped (18 active)	—	—	Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07777887recruiting Sentinel Node Identification Using Gamma and Near-Infrared Imaging in TesticulAr MaLignancies · condition mapped ALIAS · 115 trials mapped (18 active)	—	—	Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03067181Phase 3 · recruiting Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Testicular Mixed Choriocarcinoma and Embryonal Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06276491Phase 1 · recruiting Phase 1, Safety and Tolerability Study of XmAb541 in Advanced Solid Tumors · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT06060873recruiting MAGESTIC Trial: MiRNA in Detecting Active Germ Cell Tumors in Early Suspected and MetastaTIC Disease Trial · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Malignant Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT06041503Phase 2 · recruiting Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE) · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07699640NA · not yet recruiting Minimally-invasive ICG-guided Retroperitoneal Sentinel Lymph Node Dissection in the Primary Staging of Testicular Cancer Versus Standard of Care · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT02834013Phase 2 · active not recruiting Nivolumab and Ipilimumab in Treating Patients With Rare Tumors · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Testicular Non-Seminomatous Germ Cell Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT02537548NA · active not recruiting Retroperitoneal Lymph Node Dissection in Treating Patients With Testicular Seminoma · condition mapped CURATED_BROADER · 115 trials mapped (18 active)	—	—	Testicular Seminoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06191575suspended 7 Tesla MRI Neuroimaging in Testicular Cancer Patients With Hypogonadism and on Androgen Replacement Therapy · condition mapped ONTOLOGY_EXACT · 115 trials mapped (18 active)	—	—	Malignant Testicular Germ Cell Tumor	1	Observed	clinicaltrials	graph →

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