Tenosynovial Giant Cell Tumor, Diffuse Type

subtype

Identifier: CI-CAN-00004065
Entity page: /cancer/tenosynovial-giant-cell-tumor-diffuse-type ↗
Edges: 23

Neighbours: 4 drugs10 trials
Drawn: 14 of 14 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Tenosynovial Giant Cell Tumor, Diffuse Type investigated for …INVESTIGATED_FOR4 of 4
← investigated for	Vimseltinibsmall_molecule	unknown	3	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Curated	chembl	graph →
← investigated for	Pimicotinibsmall_molecule	unknown	3

Tenosynovial Giant Cell Tumor, Diffuse Type investigated in trials for …INVESTIGATED_IN_TRIALSderived4 of 4
→ investigated in trials for	Nilotinibsmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Pimicotinibsmall_molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vimseltinibsmall_molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Pexidartinibsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →

Tenosynovial Giant Cell Tumor, Diffuse Type studied in …STUDIED_INderived10 of 15show all (up to 200)
→ studied in	NCT07707882Phase 2 · not yet recruiting Neoadjuvant Pimicotinib Combined With Surgery Versus Upfront Surgery for Diffuse Tenosynovial Giant Cell Tumor · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT03069469Phase 1/Phase 2 · active not recruiting Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT05804045Phase 3 · active not recruiting Study of Pimicotinib (ABSK021) for Tenosynovial Giant Cell Tumor (MANEUVER) · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT05059262Phase 3 · active not recruiting Study of Vimseltinib for Tenosynovial Giant Cell Tumor · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT01207492Phase 2 · completed Nilotinib in Patients With Relapsed or Metastatic Pigmented Villonodular Synovitis/Tenosynovial Giant Cell Tumor/Diffuse-Type Giant Cell Tumor · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT05349643Phase 2 · completed A Study to Evaluate Safety and Efficacy of AMB-05X Injections in Subjects With TGCT · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT04731675Phase 2 · completed An Open-Label Study of Intra-articular AMB-05X Injections in Subjects With Tenosynovial Giant Cell Tumor of the Knee · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT04938180Phase 2 · terminated A Phase 2 Study of Intravenous AMB-05X in Tenosynovial Giant Cell Tumor Patients · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT04952896completed Clinical Study of Magnetic Resonance Imaging and Deep Learning of Joint Synovial Disease · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →
→ studied in	NCT02371369Phase 3 · completed Phase 3 Study of Pexidartinib for Pigmented Villonodular Synovitis (PVNS) or Giant Cell Tumor of the Tendon Sheath (GCT-TS) · condition mapped ALIAS · 15 trials mapped (4 active)	—	—	Tenosynovial Giant Cell Tumor, Diffuse Type	1	Observed	clinicaltrials	graph →

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