Optic Nerve Glioma

subtype

Identifier: CI-CAN-00003475
Entity page: /cancer/optic-nerve-glioma ↗
Edges: 21

Neighbours: 8 drugs9 trials
Drawn: 17 of 17 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Optic Nerve Glioma investigated for …INVESTIGATED_FOR4 of 4
← investigated for	Temozolomidesmall_molecule	unknown	3	Optic Nerve Glioma	1	Curated	chembl	graph →
← investigated for	Etoposidesmall_molecule	unknown	2

Optic Nerve Glioma investigated in trials for …INVESTIGATED_IN_TRIALSderived8 of 8
→ investigated in trials for	Temozolomidesmall_molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Selumetinibsmall_molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vincristinesmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Etoposidesmall_molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Irinotecansmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →

Optic Nerve Glioma investigated in trials for …INVESTIGATED_IN_TRIALSderived8 of 8

→ investigated in trials for

Temozolomidesmall_molecule

3 trials (1 active) · roll-up of the cancer and its descendants

—

Optic Nerve Glioma studied in …STUDIED_INderived9 of 9
→ studied in	NCT01837862Phase 1/Phase 2 · active not recruiting A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04648462recruiting Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02372409Phase 2 · terminated Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors · condition mapped PROBABILISTIC · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05278715Phase 2 · recruiting Modified CV Regimen in Optic Pathway Glioma · condition mapped PROBABILISTIC · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03326388Phase 1/Phase 2 · completed Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02839720Phase 2 · completed Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01800032completed PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1) · condition mapped PROBABILISTIC · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01260103Phase 3 · withdrawn Phase 3 Study of ANP Therapy vs. TMZ for Optic Pathway Glioma · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02976441early Phase 1 · withdrawn Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas · condition mapped ONTOLOGY_EXACT · 9 trials mapped (3 active)	—	—	Optic Nerve Glioma	1	Observed	clinicaltrials	graph →

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