Meningeal Carcinomatosis

Observed

→ investigated in trials for

Methotrexatesmall_molecule

4 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Bevacizumabmonoclonal antibody

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Dexamethasonesmall_molecule

3 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Firmonertinibsmall molecule

3 trials (2 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Osimertinibsmall molecule

3 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Aumolertinibsmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Chemotherapy

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Cytarabinesmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Durvalumabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Ipilimumabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Lenvatinibsmall_molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Nivolumabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Pembrolizumabmonoclonal_antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Sintilimabmonoclonal antibody

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Temozolomidesmall molecule

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Thiotepasmall molecule

1 trials (1 active) · roll-up of the cancer and its descendants

—

Observed

→ investigated in trials for

Trastuzumabmonoclonal antibody

1 trials (0 active) · roll-up of the cancer and its descendants

—

Observed

Meningeal Carcinomatosis studied in …STUDIED_INderived10 of 59show all (up to 200)
→ studied in	NCT06462222Phase 1/Phase 2 · active not recruiting Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT07833657Phase 2 · not yet recruiting Combined Intrathecal and Systemic Therapy With Trastuzumab Rezetecan for Leptomeningeal Metastases · condition mapped PROBABILISTIC · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT06762080Phase 1/Phase 2 · active not recruiting Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT06809530Phase 1/Phase 2 · active not recruiting Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis · condition mapped PROBABILISTIC · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT07778940Phase 2 · not yet recruiting Thiotepa Administration Via Ommaya Reservoir for Leptomeningeal Metastases in Non-Small Cell Lung Cancer Resistant to EGFR-TKI. · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT06812871Phase 2 · completed High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT05184816Phase 1 · recruiting A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT07702305Phase 1 · not yet recruiting Safety and Efficacy of Intrathecal Sacituzumab Tirumotecan for Leptomeningeal Metastasis in EGFR-TKI-Resistant Non-Small Cell Lung Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT07674693Phase 1 · not yet recruiting Phase 1 Study of WBRT or PCSI With REYOBIQ for Leptomeningeal Metastases · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →
→ studied in	NCT07361705Phase 1 · recruiting Zorifertinib With Osimertinib for NSCLC With Meningeal Progression · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)	—	—	Meningeal Carcinomatosis	1	Observed	clinicaltrials	graph →

Meningeal Carcinomatosis studied in …STUDIED_INderived10 of 59show all (up to 200)

→ studied in

NCT06462222Phase 1/Phase 2 · active not recruiting

Immune Checkpoint Inhibitor Combined With Pemetrexed Intrathecal Injection for Leptomeningeal Metastasis From Solid Tumors · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT07833657Phase 2 · not yet recruiting

Combined Intrathecal and Systemic Therapy With Trastuzumab Rezetecan for Leptomeningeal Metastases · condition mapped PROBABILISTIC · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT06762080Phase 1/Phase 2 · active not recruiting

Intrathecal Combination of Programmed Death-1 (PD-1)/Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Bispecific Antibody and Pemetrexed for Leptomeningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT06809530Phase 1/Phase 2 · active not recruiting

Intrathecal Dual Checkpoint Inhibitor (PD-1 and CTLA-4) in Combination With Pemetrexed for Leptomeningeal Metastasis · condition mapped PROBABILISTIC · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT07778940Phase 2 · not yet recruiting

Thiotepa Administration Via Ommaya Reservoir for Leptomeningeal Metastases in Non-Small Cell Lung Cancer Resistant to EGFR-TKI. · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT06812871Phase 2 · completed

High-dose Furmonertinib Combined With Bevacizumab and Intrathecal Pemetrexed Chemotherapy in Patients With EGFR-mutated Non-small Cell Lung Cancer and Meningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT05184816Phase 1 · recruiting

A Study of Deferoxamine (DFO) in People With Leptomeningeal Metastasis · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT07702305Phase 1 · not yet recruiting

Safety and Efficacy of Intrathecal Sacituzumab Tirumotecan for Leptomeningeal Metastasis in EGFR-TKI-Resistant Non-Small Cell Lung Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed

→ studied in

NCT07674693Phase 1 · not yet recruiting

Phase 1 Study of WBRT or PCSI With REYOBIQ for Leptomeningeal Metastases · condition mapped ONTOLOGY_EXACT · 59 trials mapped (30 active)

—

Observed