Malignant Pineal Region Neoplasm — knowledge graph · CancerIndex

Knowledge graph · Cancer

Malignant Pineal Region Neoplasm

subtype

Identifier: CI-CAN-00008985
Entity page: /cancer/malignant-pineal-region-neoplasm ↗
Edges: 74

Neighbours: 35 drugs10 trials
Drawn: 45 of 45 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Malignant Pineal Region Neoplasm investigated in trials for …INVESTIGATED_IN_TRIALSderived35 of 35show fewer
→ investigated in trials for	Temozolomidesmall molecule 8 trials (1 active) · roll-up of the cancer and its descendants	—	—	Malignant Pineal Region Neoplasm	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Filgrastimother

Malignant Pineal Region Neoplasm studied in …STUDIED_INderived10 of 39show all (up to 200)
→ studied in	NCT04684368Phase 2 · recruiting A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineal Region Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT07087002Phase 1 · recruiting GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07390539Phase 1 · recruiting B7-H3.CD28Z.CART in CNS Neoplasms · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06368817Phase 2 · recruiting A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineal Region Germinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06942039early Phase 1 · recruiting Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06193759Phase 1 · recruiting Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07017816early Phase 1 · recruiting A Phase 0/1 Study of cDNA for TP53, Checkpoint Inhibition and Radiation in Children With Recurrent, Progressive or Refractory CNS Malignancies. · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05934630terminated Testing Cerebrospinal Fluid for Cell-free Tumor DNA in Children, Adolescents, and Young Adults With Brain Tumors · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04185038Phase 1 · recruiting Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Childhood Pineoblastoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03500991Phase 1 · active not recruiting HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors · condition mapped ONTOLOGY_EXACT · 39 trials mapped (10 active)	—	—	Pineoblastoma	1	Observed	clinicaltrials	graph →