Malignant Mediastinal Neoplasm

subtype

Identifier: CI-CAN-00001141
Entity page: /cancer/malignant-mediastinal-neoplasm ↗
Edges: 195

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Malignant Mediastinal Neoplasm approved for …APPROVED_FORderived1 of 1
← approved for	Pembrolizumabmonoclonal antibody FDA (US) · approved · 2014-09-04 · Primary Mediastinal Large B-Cell Lymphoma (PMBCL) for the treatment of adult and pediatric patients with refractory PMBCL, or who have rela…	—	approved	Primary Mediastinal Large B-Cell Lymphoma	1	Regulatory	openfda	graph →
Malignant Mediastinal Neoplasm …

Malignant Mediastinal Neoplasm studied in …STUDIED_INderived10 of 144show all (up to 200)
→ studied in	NCT04231877Phase 1 · active not recruiting Polatuzumab Vedotin and Combination Chemotherapy With or Without Glofitamab for the Treatment of Untreated Aggressive Large B-cell Lymphoma · condition mapped ONTOLOGY_EXACT · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06784167recruiting Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment · condition mapped ONTOLOGY_EXACT · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05359211Phase 1 · completed NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma · condition mapped CURATED_BROADER · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05025800Phase 1/Phase 2 · active not recruiting ALX148, Rituximab and Lenalidomide for the Treatment of Indolent and Aggressive B-cell Non-Hodgkin Lymphoma · condition mapped CURATED_BROADER · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07685938Phase 2 · recruiting Pharmacologic Therapies to Mitigate Radiation- Associated Heart Disease · condition mapped ALIAS · 144 trials mapped (79 active)	—	—	Malignant Mediastinal Neoplasm	1	Observed	clinicaltrials	graph →
→ studied in	NCT07168486Phase 1 · enrolling by invitation CD19.20.22 CAR T-cells for Patients With Relapsed/Refractory B-Cell Lymphomas · condition mapped ONTOLOGY_EXACT · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07817641NA · recruiting Proton Therapy for Mediastinal Lymphoma (PROMLY) · condition mapped ONTOLOGY_EXACT · 144 trials mapped (79 active)	—	—	Mediastinal Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05934084NA · recruiting Lifestyles Implemented-Survivorship Care Plan In Lymphoma Survivors · condition mapped ONTOLOGY_EXACT · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06830031Phase 1 · recruiting Clinical Study of C402-CD19-CAR Treatment in Subjects With Relapsed or Refractory B-cell Lymphoma · condition mapped ALIAS · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07098364Phase 1/Phase 2 · suspended ST-067 in Combination With CD19-Directed CAR T-Cell Therapy (Liso-cel) in Relapsed/Refractory Large B-Cell Lymphoma · condition mapped CURATED_BROADER · 144 trials mapped (79 active)	—	—	Primary Mediastinal Large B-Cell Lymphoma	1	Observed	clinicaltrials	graph →

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