Luminal B Breast Carcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Luminal B Breast Carcinoma

subtype

Identifier: CI-CAN-00007961
Entity page: /cancer/luminal-b-breast-carcinoma ↗
Edges: 13

Neighbours: 5 drugs8 trials
Drawn: 13 of 13 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Luminal B Breast Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived5 of 5
→ investigated in trials for	Durvalumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Luminal B Breast Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants

Luminal B Breast Carcinoma studied in …STUDIED_INderived8 of 8
→ studied in	NCT06585969Phase 3 · withdrawn A Randomised Trial Comparing Trastuzumab Deruxtecan to CDK4/6 Inhibitors in Non-luminal A, ER-positive/HER2-low Metastatic Breast Cancer · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04118062NA · completed Communicating With Patients on Cancer Resistance to Treatment: the Development of a Communication Tool. (HECTOR) · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03715959NA · completed Nipple Aspirate Fluid in Detecting Breast Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06805084active not recruiting Transcripts with Retained H/ACA Box SnoRNA Sequences As Biomarkers for Estrogen Dependence in Lum-B Breast Carcinomas · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03875573Phase 2 · active not recruiting Neo-adjuvant Chemotherapy Combined With Stereotactic Body Radiotherapy to the Primary Tumour +/- Durvalumab, +/- Oleclumab in Luminal B Breast Cancer: · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03356860Phase 1/Phase 2 · completed Safety and Efficacy of Durvalumab Combined to Neoadjuvant Chemotherapy in Localized Luminal B HER2(-) and Triple Negative Breast Cancer. · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05163106Phase 2 · completed Neoadjuvant Treatment of Locally-advanced Breast Cancer Patients With Ribociclib and Letrozole · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03860740completed Effect of Physical Exercise on Tumor Proliferation of Luminal B Breast Cancer Patients · condition mapped ALIAS · 8 trials mapped (2 active)	—	—	Luminal B Breast Carcinoma	1	Observed	clinicaltrials	graph →