Laryngeal Squamous Cell Carcinoma

subtype

Identifier: CI-CAN-00005726
Entity page: /cancer/laryngeal-squamous-cell-carcinoma ↗
Edges: 188

Neighbours: 1 genes1 variants16 drugs10 trials
Drawn: 28 of 28 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Laryngeal Squamous Cell Carcinoma predicts response to …PREDICTS_RESPONSE_TO1 of 1
in context · predicts response to	BRAF V600ESNV → predicts response to Vemurafenib	sensitivity	C	Laryngeal Squamous Cell Carcinoma	1	Curated	civic	graph →
Laryngeal Squamous Cell Carcinoma associated with …

Laryngeal Squamous Cell Carcinoma investigated for …INVESTIGATED_FOR1 of 1
← investigated for	Vemurafenibsmall_molecule	supports	C	Laryngeal Squamous Cell Carcinoma	1	Curated	civic	graph →

Laryngeal Squamous Cell Carcinoma investigated for …INVESTIGATED_FOR1 of 1

← investigated for

Vemurafenibsmall_molecule

supports

Laryngeal Squamous Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 47show all (up to 200)
→ investigated in trials for	Cisplatinsmall molecule 29 trials (11 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	29	Observed	clinicaltrials	graph →
→ investigated in trials for	Cetuximabmonoclonal antibody 19 trials (3 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	19	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 16 trials (9 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	16	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 14 trials (13 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	14	Observed	clinicaltrials	graph →
→ investigated in trials for	Erlotinib Hydrochloridesmall molecule 12 trials (0 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall molecule 9 trials (3 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Paclitaxelsmall molecule 9 trials (5 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 6 trials (2 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Fluorouracilsmall molecule 5 trials (2 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Capecitabinesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Cemiplimabmonoclonal antibody 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Lapatinibsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Sorafenib Tosylatesmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Vorinostatsmall molecule 3 trials (0 active) · roll-up of the cancer and its descendants	—	—	Laryngeal Squamous Cell Carcinoma	3	Observed	clinicaltrials	graph →

Laryngeal Squamous Cell Carcinoma studied in …STUDIED_INderived10 of 138show all (up to 200)
→ studied in	NCT06589804Phase 3 · recruiting Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05136196Phase 2 · recruiting BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06980038Phase 2 · recruiting Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer · condition mapped ONTOLOGY_EXACT · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04671667Phase 2 · recruiting Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05172245Phase 1 · recruiting Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05172258Phase 2 · active not recruiting Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02734537Phase 2 · recruiting Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery · condition mapped ONTOLOGY_EXACT · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05721755Phase 3 · active not recruiting Combining Radiation Therapy With Immunotherapy for the Treatment of Metastatic Squamous Cell Carcinoma of the Head and Neck · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05752149Phase 2 · recruiting Fluorescence-guided Surgery in Laryngeal- and Hypopharyngeal Cancer: a Feasibility Trial · condition mapped ALIAS · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07156227Phase 1 · recruiting Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma · condition mapped CURATED_BROADER · 138 trials mapped (44 active)	—	—	Laryngeal Squamous Cell Carcinoma	1	Observed	clinicaltrials	graph →

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