Invasive Bladder Urothelial Carcinoma

subtype

Identifier: CI-CAN-00005609
Entity page: /cancer/invasive-bladder-urothelial-carcinoma ↗
Edges: 73

Neighbours: 1 genes1 variants16 drugs10 trials
Drawn: 28 of 28 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Invasive Bladder Urothelial Carcinoma predicts response to …PREDICTS_RESPONSE_TO1 of 1
in context · predicts response to	TSC1 Frameshift Truncationindel → predicts response to Everolimus	sensitivity	C	Invasive Bladder Urothelial Carcinoma	1	Curated	civic	graph →
Invasive Bladder Urothelial Carcinoma …

Invasive Bladder Urothelial Carcinoma investigated for …INVESTIGATED_FOR1 of 1
← investigated for	Everolimussmall_molecule	supports	C	Invasive Bladder Urothelial Carcinoma	1	Curated	civic	graph →

Invasive Bladder Urothelial Carcinoma investigated for …INVESTIGATED_FOR1 of 1

← investigated for

Everolimussmall_molecule

supports

Invasive Bladder Urothelial Carcinoma

Curated

Invasive Bladder Urothelial Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 25show all (up to 200)
→ investigated in trials for	Gemcitabinesmall molecule 9 trials (7 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	9	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 8 trials (6 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 8 trials (7 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Durvalumabmonoclonal antibody 5 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	5	Observed	clinicaltrials	graph →
→ investigated in trials for	Enfortumab Vedotinadc 4 trials (4 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 4 trials (4 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Cabozantinibsmall molecule 3 trials (3 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Avelumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fluorouracilsmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Methotrexatesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Mitomycinsmall molecule 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Tremelimumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Vinblastinesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Invasive Bladder Urothelial Carcinoma	2	Observed	clinicaltrials	graph →

Invasive Bladder Urothelial Carcinoma studied in …STUDIED_INderived10 of 45show all (up to 200)
→ studied in	NCT03866382Phase 2 · recruiting Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05987241Phase 2/Phase 3 · recruiting Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07061964Phase 2 · recruiting Combining Immunotherapy and Radiation Therapy to Help Patients Avoid Bladder Removal After Treatment Shrinks Muscle Invasive Bladder Cancer, BRIGHT Trial · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06770582Phase 2 · recruiting Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Non-Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06605404recruiting Pan-tumor MRD Study · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07332351Phase 2 · not yet recruiting Neoadjuvant Intravesical Nadofaragene Firadenovec With Gemcitabine, Cisplatin and Durvalumab for the Treatment of Muscle Invasive Bladder Cancer, TRIFECTA Trial · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07667335Phase 1/Phase 2 · recruiting Enfortumab Vedotin, Pembrolizumab and Quemliclustat for the Treatment of Unresectable Locally Advanced and Metastatic Urothelial Cancer · condition mapped CURATED_BROADER · 45 trials mapped (31 active)	—	—	Invasive Bladder Giant Cell Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07822373Phase 2 · not yet recruiting A Phase 2 Study Evaluating Bladder Preservation With Enfortumab Vedotin Plus Pembrolizumab in Patients With Muscle-Invasive Urothelial Cancer · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02812420early Phase 1 · active not recruiting Durvalumab and Tremelimumab in Treating Patients With Muscle-Invasive, High-Risk Urothelial Cancer That Cannot Be Treated With Cisplatin-Based Therapy Before Surgery · condition mapped ALIAS · 45 trials mapped (31 active)	—	—	Invasive Bladder Sarcomatoid Urothelial Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06503614Phase 2 · recruiting A Trial of Durvalumab (MEDI4736) Plus Monalizumab in Non-Muscle-Invasive Bladder Cancer · condition mapped ONTOLOGY_EXACT · 45 trials mapped (31 active)	—	—	Non-Muscle Invasive Bladder Urothelial Carcinoma	1	Observed	clinicaltrials	graph →

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