Hereditary Renal Cell Carcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Hereditary Renal Cell Carcinoma

subtype

Identifier: CI-CAN-00002869
Entity page: /cancer/hereditary-renal-cell-carcinoma ↗
Edges: 19

Neighbours: 7 drugs10 trials
Drawn: 17 of 17 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Hereditary Renal Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived7 of 7
→ investigated in trials for	Bevacizumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Hereditary Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Erlotinibsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants

Hereditary Renal Cell Carcinoma studied in …STUDIED_INderived10 of 12show all (up to 200)
→ studied in	NCT04981509Phase 2 · recruiting Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer · condition mapped ONTOLOGY_EXACT · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00001238recruiting Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant Disorders · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Hereditary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07716735Phase 1 · not yet recruiting Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer · condition mapped ONTOLOGY_EXACT · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07300241Phase 1 · recruiting Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Von Hippel Lindau Syndrome-Associated Clear Cell Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03401788Phase 2 · active not recruiting A Phase 2 Study of Belzutifan (PT2977, MK-6482) for the Treatment of Von Hippel Lindau (VHL) Disease-Associated Renal Cell Carcinoma (RCC) (MK-6482-004) · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Von Hippel Lindau Syndrome-Associated Clear Cell Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04623502NA · recruiting An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01130519Phase 2 · completed A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03749980recruiting MyVHL: Patient Natural History Study · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05534854unknown Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes · condition mapped ALIAS · 12 trials mapped (7 active)	—	—	Hereditary Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04603365Phase 2 · withdrawn Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer · condition mapped ONTOLOGY_EXACT · 12 trials mapped (7 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →