Hereditary Leiomyomatosis and Renal Cell Carcinoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Hereditary Leiomyomatosis and Renal Cell Carcinoma

subtype

Identifier: CI-CAN-00005495
Entity page: /cancer/hereditary-leiomyomatosis-and-renal-cell-carcinoma ↗
Edges: 13

Neighbours: 5 drugs8 trials
Drawn: 13 of 13 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Hereditary Leiomyomatosis and Renal Cell Carcinoma investigated in trials for …INVESTIGATED_IN_TRIALSderived5 of 5
→ investigated in trials for	Bevacizumabmonoclonal antibody 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Erlotinibsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants

Hereditary Leiomyomatosis and Renal Cell Carcinoma studied in …STUDIED_INderived8 of 8
→ studied in	NCT04981509Phase 2 · recruiting Testing of Bevacizumab, Erlotinib, and Atezolizumab in Combination for Advanced-Stage Kidney Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07716735Phase 1 · not yet recruiting Mercaptopurine for the Treatment of Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC), Uterine/Cutaneous Leiomyomas, and Kidney Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04623502NA · recruiting An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy · condition mapped ALIAS · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT01130519Phase 2 · completed A Phase II Study of Bevacizumab and Erlotinib in Subjects With Advanced Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) or Sporadic Papillary Renal Cell Cancer · condition mapped ALIAS · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03749980recruiting MyVHL: Patient Natural History Study · condition mapped ALIAS · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05534854unknown Frequency, Clinical Phenotype and Genetic Analysis of Heritable Kidney Cancer Syndromes · condition mapped ALIAS · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04603365Phase 2 · withdrawn Pamiparib and Temozolomide for the Treatment of Hereditary Leiomyomatosis and Renal Cell Cancer · condition mapped ONTOLOGY_EXACT · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT00971620Phase 2 · completed Randomized Pilot Study for the Treatment of Cutaneous Leiomyomas With Botulinum Toxin · condition mapped ALIAS · 8 trials mapped (4 active)	—	—	Hereditary Leiomyomatosis and Renal Cell Carcinoma	1	Observed	clinicaltrials	graph →