Female Reproductive System Carcinosarcoma

subtype

Identifier: CI-CAN-00002686
Entity page: /cancer/female-reproductive-system-carcinosarcoma ↗
Edges: 199

Neighbours: 15 genes15 drugs10 trials
Drawn: 40 of 40 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Female Reproductive System Carcinosarcoma altered in cohorts of …ALTERED_INderived15 of 101show all (up to 200)
← altered in cohorts of	TP53 52 / 57 cases (91 %) · ssm · TCGA-UCS · largest of 4 cohorts	—	—	Uterine Carcinosarcoma	4	Observed	gdc	graph →
← altered in cohorts of	MELTF 46 / 57 cases (81 %) · ssm · TCGA-UCS

Female Reproductive System Carcinosarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 39show all (up to 200)
→ investigated in trials for	Paclitaxelsmall molecule 12 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	12	Observed	clinicaltrials	graph →
→ investigated in trials for	Bevacizumabmonoclonal antibody 10 trials (2 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	10	Observed	clinicaltrials	graph →
→ investigated in trials for	Carboplatinsmall molecule 8 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamidesmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Gemcitabinesmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Olaparibsmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Aldesleukinother 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Cisplatinsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Docetaxelsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Doxorubicinsmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 2 trials (1 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Rucaparibsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Sorafenib Tosylatesmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Female Reproductive System Carcinosarcoma	2	Observed	clinicaltrials	graph →

Female Reproductive System Carcinosarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 39show all (up to 200)

→ investigated in trials for

Paclitaxelsmall molecule

12 trials (1 active) · roll-up of the cancer and its descendants

—

Female Reproductive System Carcinosarcoma

Observed

Female Reproductive System Carcinosarcoma studied in …STUDIED_INderived10 of 59show all (up to 200)
→ studied in	NCT05256225Phase 3 · recruiting Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Uterine Corpus Malignant Mixed Mesodermal (Mullerian) Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT05920798Phase 1/Phase 2 · active not recruiting Vaccine Therapy Plus Pembrolizumab in Treating Advanced Ovarian, Fallopian Tube, or Primary Peritoneal Cavity Cancer · condition mapped ALIAS · 59 trials mapped (19 active)	—	—	Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT02101775Phase 2 · active not recruiting Gemcitabine Hydrochloride With or Without WEE1 Inhibitor MK-1775 in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Ovarian Malignant Mixed Mesodermal (Mullerian) Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03651206Phase 2/Phase 3 · recruiting Recurrent Ovarian CarcinoSarcoma Anti-pd-1 Niraparib · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Ovarian Carcinosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07741968NA · recruiting A Blended e-Health Intervention to Improve Fear of Progression in Women With Gynecologic or Breast Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Ovarian Carcinosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06580314Phase 3 · recruiting Testing Olaparib for One or Two Years, With or Without Bevacizumab, to Treat Ovarian Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03120624Phase 1 · active not recruiting VSV-hIFNbeta-NIS With or Without Ruxolitinib Phosphate in Treating Stage IV or Recurrent Endometrial Cancer · condition mapped CURATED_BROADER · 59 trials mapped (19 active)	—	—	Uterine Corpus Carcinosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04092270Phase 1 · active not recruiting A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Fallopian Tube Malignant Mixed Mesodermal (Mullerian) Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT03449108Phase 2 · active not recruiting LN-145 or LN-145-S1 in Treating Patients With Relapsed or Refractory Ovarian Cancer, Triple Negative Breast Cancer (TNBC), Anaplastic Thyroid Cancer, Osteosarcoma, or Other Bone and Soft Tissue Sarcomas · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Ovarian Carcinosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05049538recruiting Determine the Utility of Liquid Biopsies and Tumor Molecular Profiling in Predicting Recurrence in Endometrial Cancers · condition mapped ONTOLOGY_EXACT · 59 trials mapped (19 active)	—	—	Uterine Corpus Carcinosarcoma	1	Observed	clinicaltrials	graph →

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