Epithelioid Sarcoma

subtype

Identifier: CI-CAN-00002604
Entity page: /cancer/epithelioid-sarcoma ↗
Edges: 56

Neighbours: 1 genes15 drugs10 trials
Drawn: 26 of 26 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Epithelioid Sarcoma approved for …APPROVED_FOR1 of 1
← approved for	Tazemetostatsmall_molecule	supports	FDA ORIG	Epithelioid Sarcoma	1	Regulatory	openfda	graph →
Epithelioid Sarcoma associated with …ASSOCIATED_WITH1 of 1
← associated with

Epithelioid Sarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 21show all (up to 200)
→ investigated in trials for	Doxorubicinsmall molecule 8 trials (2 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	8	Observed	clinicaltrials	graph →
→ investigated in trials for	Tazemetostatsmall_molecule 6 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	6	Observed	clinicaltrials	graph →
→ investigated in trials for	Ifosfamidesmall molecule 4 trials (2 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	4	Observed	clinicaltrials	graph →
→ investigated in trials for	Nivolumabmonoclonal antibody 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Pazopanibsmall molecule 3 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Cixutumumabmonoclonal antibody 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Ipilimumabmonoclonal antibody 2 trials (2 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Atezolizumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Cemiplimabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Dasatinibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Gemcitabinesmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Pembrolizumabmonoclonal antibody 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Ribociclibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Romidepsinother 1 trials (0 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ investigated in trials for	Selinexorsmall molecule 1 trials (1 active) · roll-up of the cancer and its descendants	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →

Epithelioid Sarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 21show all (up to 200)

→ investigated in trials for

Doxorubicinsmall molecule

8 trials (2 active) · roll-up of the cancer and its descendants

—

Epithelioid Sarcoma studied in …STUDIED_INderived10 of 33show all (up to 200)
→ studied in	NCT06444880Phase 2 · active not recruiting Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06239272Phase 1/Phase 2 · recruiting NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS) · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03069378Phase 2 · active not recruiting A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05286801Phase 1/Phase 2 · active not recruiting Tiragolumab and Atezolizumab for the Treatment of Relapsed or Refractory SMARCB1 or SMARCA4 Deficient Tumors · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03874455no longer available Tazemetostat Expanded Access Program for Adults With Solid Tumors · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04225429no longer available Tazemetostat Expanded Access Program for Adults With Epithelioid Sarcoma · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04416568Phase 2 · active not recruiting Study of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT06625190Phase 1/Phase 2 · recruiting Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT02180867Phase 2/Phase 3 · completed Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT05407441Phase 1/Phase 2 · active not recruiting Tazemetostat+Nivo/Ipi in INI1-Neg/SMARCA4-Def Tumors · condition mapped ONTOLOGY_EXACT · 33 trials mapped (11 active)	—	—	Epithelioid Sarcoma	1	Observed	clinicaltrials	graph →

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