Childhood Osteosarcoma — knowledge graph · CancerIndex

Knowledge graph · Cancer

Childhood Osteosarcoma

subtype

Identifier: CI-CAN-00002305
Entity page: /cancer/childhood-osteosarcoma ↗
Edges: 8

Neighbours: 3 drugs5 trials
Drawn: 8 of 8 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

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Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Osteosarcoma investigated in trials for …INVESTIGATED_IN_TRIALSderived3 of 3
→ investigated in trials for	Cyclophosphamidesmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants	—	—	Childhood Osteosarcoma	3	Observed	clinicaltrials	graph →
→ investigated in trials for	Fludarabinesmall molecule 3 trials (2 active) · roll-up of the cancer and its descendants

Childhood Osteosarcoma studied in …STUDIED_INderived5 of 5
→ studied in	NCT03210714Phase 2 · active not recruiting Erdafitinib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With FGFR Mutations (A Pediatric MATCH Treatment Trial) · condition mapped CURATED_BROADER · 5 trials mapped (3 active)	—	—	Childhood Osteosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07428993Phase 2 · recruiting Evaluating Efficacy of B7-H3-CAR T Cells Administered at the End of Upfront Map Chemotherapy in Patients With Newly Diagnosed High-Risk Osteosarcoma · condition mapped ALIAS · 5 trials mapped (3 active)	—	—	Childhood Osteosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT04539366Phase 1 · suspended Testing a New Immune Cell Therapy, GD2-Targeted Modified T-cells (GD2CART), in Children, Adolescents, and Young Adults With Relapsed/Refractory Osteosarcoma and Neuroblastoma, GD2-CAR PERSIST Trial · condition mapped CURATED_BROADER · 5 trials mapped (3 active)	—	—	Childhood Osteosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT07222735Phase 1 · recruiting Hypofractionated Radiation in Combination With B7-H3-CAR T Cells for Pediatric Patients With Relapsed/Refractory Sarcomas · condition mapped ONTOLOGY_EXACT · 5 trials mapped (3 active)	—	—	Childhood Osteosarcoma	1	Observed	clinicaltrials	graph →
→ studied in	NCT03298971unknown The Impact of Cancer on the Physical and Psychosocial Well-being Among Childhood Osteosarcoma Survivors · condition mapped ONTOLOGY_EXACT · 5 trials mapped (3 active)	—	—	Childhood Osteosarcoma	1	Observed	clinicaltrials	graph →