Childhood Central Nervous System Yolk Sac Tumor — knowledge graph · CancerIndex

Knowledge graph · Cancer

Childhood Central Nervous System Yolk Sac Tumor

subtype

Identifier: CI-CAN-00002223
Entity page: /cancer/childhood-central-nervous-system-yolk-sac-tumor ↗
Edges: 15

Neighbours: 9 drugs6 trials
Drawn: 15 of 15 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,147 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

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Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Central Nervous System Yolk Sac Tumor investigated in trials for …INVESTIGATED_IN_TRIALSderived9 of 9
→ investigated in trials for	Vorinostatsmall molecule 2 trials (0 active) · roll-up of the cancer and its descendants	—	—	Childhood Central Nervous System Yolk Sac Tumor	2	Observed	clinicaltrials	graph →
→ investigated in trials for	Bortezomibsmall molecule 1 trials (0 active) · roll-up of the cancer and its descendants

Childhood Central Nervous System Yolk Sac Tumor studied in …STUDIED_INderived6 of 6
→ studied in	NCT01088763Phase 1 · terminated Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00387920Phase 1 · completed Sunitinib in Treating Young Patients With Refractory Solid Tumors · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00929903Phase 1 · completed Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00994500Phase 1 · completed Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT00281944Phase 1 · completed Combination Chemotherapy in Treating Young Patients With Advanced Solid Tumors · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →
→ studied in	NCT01076530Phase 1 · completed Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors · condition mapped ONTOLOGY_EXACT · 6 trials mapped (0 active)	—	—	Childhood Central Nervous System Yolk Sac Tumor	1	Observed	clinicaltrials	graph →