Childhood Acute Myeloid Leukemia

hematologic malignancy

Identifier: CI-CAN-00004822
Entity page: /cancer/childhood-acute-myeloid-leukemia ↗
Edges: 191

Neighbours: 15 drugs10 trials
Drawn: 25 of 25 neighbours (cap 60); table lists every fetched edge

Accepted: cancer:<slug>, gene:<symbol>, variant:<slug>, drug:<slug>, trial:<NCT id>, or a bare CI id. Find slugs with search.

Most connectedLung Non-Small Cell Carcinoma 3,149 Malignant Colorectal Neoplasm 1,866 ABL1 298 EGFR 276 Imatinib 450 Dasatinib 321

Neighbourhood

Radial view

Focus at the centre; neighbours grouped by entity type. Click a node to re-centre the graph on it; ↗ opens the entity page. Hover a spoke for relationship, evidence level, cancer context and source.

Edges

Every edge, grouped by relationship

Source-native edges first (aggregated per neighbour, direction, evidence level and source), then derived registry links. Up to 15 per relationship (10 trials); “show all” raises one group to 200.

Relationship	Neighbour	Direction	Evidence level	Cancer context	Support	Claim	Source	Expand
Childhood Acute Myeloid Leukemia investigated in trials for …INVESTIGATED_IN_TRIALSderived15 of 63show all (up to 200)
→ investigated in trials for	Fludarabinesmall molecule 39 trials (5 active) · roll-up of the cancer and its descendants	—	—	Childhood Acute Myeloid Leukemia	39	Observed	clinicaltrials	graph →
→ investigated in trials for	Cyclophosphamide

Childhood Acute Myeloid Leukemia studied in …STUDIED_INderived10 of 128show all (up to 200)
→ studied in	NCT05857969Phase 1 · recruiting Ex Vivo Drug Sensitivity Testing and Multi-Omics Profiling · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06247787Phase 1 · recruiting A Study to Find the Highest Dose of Imetelstat in Combination With Fludarabine and Cytarabine for Patients With AML, MDS or JMML That Has Come Back or Does Not Respond to Therapy · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06158828Phase 1/Phase 2 · recruiting Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07059975early Phase 1 · recruiting UPDATE AML: UPdated Disease Monitoring And Treatment for Enhanced Outcomes for Pediatric AML · condition mapped ALIAS · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07770698Phase 1/Phase 2 · not yet recruiting A Study of Sonrotoclax (BGB-11417) in Children With Relapsed or Refractory Acute Myeloid Leukemia and B-cell Acute Lymphoblastic Leukemia · condition mapped ALIAS · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07756034recruiting Tempus Open Link for Individual Voices in Innovative Analytics Registry: Platform Protocol for Multimodal Real-World Evidence in Cancer · condition mapped ALIAS · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT06609928Phase 1 · recruiting FH-FOLR1 Chimeric Antigen Receptor T Cell Therapy for Treating Pediatric Patients With Relapsed or Refractory Acute Myeloid Leukemia · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT07749976Phase 1/Phase 2 · not yet recruiting GRACE: A Phase 1/2a Study of VTRU200 in Relapsed/Refractory AML, High-risk MDS, DLBCL Post CART Failure and Advanced Solid Tumors · condition mapped ALIAS · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT02094794Phase 2 · active not recruiting Total Marrow and Lymphoid Irradiation and Chemotherapy Before DSCT in Treating Patients With High-Risk ALL or AML · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →
→ studied in	NCT02220985Phase 2 · completed Selective Depletion of CD45RA+ T Cells From Allogeneic Peripheral Blood Stem Cell Grafts From HLA-Matched Related and Unrelated Donors in Preventing GVHD · condition mapped CURATED_BROADER · 128 trials mapped (17 active)	—	—	Childhood Acute Myeloid Leukemia	1	Observed	clinicaltrials	graph →

Radial view

Every edge, grouped by relationship

Strongest chains